TABLE 2.
The top 15 enriched GO-CC terms of the methylated DEGs.
| ID | Term | Count | p value | Fdr | Enrichment score | Genes |
|---|---|---|---|---|---|---|
| GO:0070062 | extracellular exosome | 28 | 0.000489349 | 0.058596438 | 3.310381497 | AOX1//CD248//CD74//CLIC6//EFEMP1//FSTL1//HLAE//HPRT1//ISLR//KRT7//MYO1C//PGK1//PLCD1//PPL//PRELP//PSMB2//RAB5C//RBMX//RBP4//RPS9//SERPING1//SNRPD2//STEAP4//TGFBR3//THY1//VAMP8//VMO1//WWP1 |
| GO:0043202 | lysosomal lumen | 5 | 0.000536885 | 0.058596438 | 3.27011879 | CD74//CTSK//FMOD//PDGFRB//PRELP |
| GO:1903561 | extracellular vesicle | 28 | 0.000574475 | 0.058596438 | 3.240728952 | AOX1//CD248//CD74//CLIC6//EFEMP1//FSTL1//HLAE//HPRT1//ISLR//KRT7//MYO1C//PGK1//PLCD1//PPL//PRELP//PSMB2//RAB5C//RBMX//RBP4//RPS9//SERPING1//SNRPD2//STEAP4//TGFBR3//THY1//VAMP8//VMO1//WWP1 |
| GO:0071556 | integral component of lumenal side of endoplasmic reticulum membrane | 3 | 0.001063195 | 0.081334418 | 2.973387073 | CD74//HLA-A//HLA-E |
| GO:0098576 | lumenal side of membrane | 3 | 0.001847225 | 0.107001025 | 2.733480203 | CD74//HLA-A//HLA-E |
| GO:0042612 | MHC class I protein complex | 2 | 0.002098059 | 0.107001025 | 2.678182239 | HLA-A//HLA-E |
| GO:0031901 | early endosome membrane | 5 | 0.004523861 | 0.188769752 | 2.344490779 | HLA-A//HLA-E//RAB5C//STEAP4//VAMP8 |
| GO:0030134 | COPII-oated ER to Golgi transport vesicle | 4 | 0.004935157 | 0.188769752 | 2.306699035 | CD74//HLA-A//HLA-E//KLHL21 |
| GO:0045121 | membrane raft | 7 | 0.007108918 | 0.191296621 | 2.148196479 | GPM6B//HCK//MYO1C//PGK1//PTGIS//SULF1//THY1 |
| GO:0031982 | vesicle | 39 | 0.00714269 | 0.191296621 | 2.146138182 | AOX1//APH1B//C1QTNF5//CD248//CD74//CLIC6//CTSK//DDOST//EFEMP1//FSTL1//HCK//HLA-A//HLA-E//HPRT1//ISLR//KLHL21//KRT7//LHFPL2//MYO1C//PDGFRB//PGK1//PLCD1//PPL//PRELP//PSMB2//RAB5C//RBMX//RBP4//RPS9//SERPING1//SNRPD2//STEAP4//TAOK2//TGFBR3//THY1//TRAK1//VAMP8//VMO1//WWP1 |
| GO:0062023 | collagen-containing extracellular matrix | 8 | 0.008003387 | 0.191296621 | 2.096726203 | COL21A1//EFEMP1//FMOD//LAMA2//PODN//PRELP//SERPING1//SULF1 |
| GO:0035577 | azurophil granule membrane | 3 | 0.008126981 | 0.191296621 | 2.090070775 | DDOST//RAB5C//VAMP8 |
| GO:0012507 | ER to Golgi transport vesicle membrane | 3 | 0.009313018 | 0.203555962 | 2.030909563 | CD74//HLA-A//HLA-E |
| GO:0005689 | U12-type spliceosomal complex | 2 | 0.014088255 | 0.221781522 | 1.851142802 | LSM7//SNRPD2 |
| GO:0,045,335 | phagocytic vesicle | 4 | 0.014495524 | 0.221781522 | 1.838766071 | HLA-A//HLA-E//MYO1C//VAMP8 |
CC, cellular component.