TABLE 3.

The top 15 enriched GO-MF terms of the methylated DEGs.

ID	Term	Count	p value	Fdr	Enrichment score	Genes
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3	0.000582628	0.178742232	3.234608341	FMOD//PODN//PRELP
GO:0042379	chemokine receptor binding	4	0.001467647	0.178742232	2.833378248	CXCL5//CXCL6//PF4V1//STAT3
GO:0008009	chemokine activity	3	0.006012581	0.178742232	2.220939072	CXCL5//CXCL6//PF4V1
GO:0000400	four-way junction DNA binding	2	0.006337918	0.178742232	2.198053411	HMGB3//RAD51C
GO:0070888	E-box binding	3	0.006722494	0.178742232	2.172469604	HDAC1//NONO//TWIST1
GO:0008201	heparin binding	5	0.009601926	0.178742232	2.017641638	CXCL6//FSTL1//PF4V1//PRELP//TGFBR3
GO:0016301	kinase activity	12	0.015562307	0.178966531	1.80792602	DYRK3//EFEMP1//HCK//NME5//PDGFRB//PDK3//PGK1//PRPS2//RIPK3//TAOK2//TGFBR3//TK1
GO:0005126	cytokine receptor binding	6	0.019817892	0.197152983	1.702942534	CXCL5//CXCL6//GDF5//PF4V1//STAT3//TGFBR3
GO:0004713	protein tyrosine kinase activity	4	0.021126016	0.197152983	1.675182406	DYRK3//EFEMP1//HCK//PDGFRB
GO:0042605	peptide antigen binding	2	0.02565908	0.207534353	1.590758917	HLA-A//HLA-E
GO:0071949	FAD binding	2	0.02565908	0.207534353	1.590758917	AOX1//STEAP4
GO:0001103	RNA polymerase II repressing transcription factor binding	2	0.028634818	0.207534353	1.543105573	HDAC1//STAT3
GO:0008200	ion channel inhibitor activity	2	0.033342478	0.21073612	1.477002122	ENSA//VAMP8
GO:0016248	channel inhibitor activity	2	0.034974515	0.21073612	1.456248298	ENSA//VAMP8
GO:0043531	ADP binding	2	0.034974515	0.21073612	1.456248298	PGK1//PRPS2

MF, molecular function.