TABLE 4.

The top 15 enriched KEGG pathway terms of the methylated DEGs.

ID	Term	Count	p value	Fdr	Enrichment score	Genes
hsa04062	Chemokine signaling pathway	6	0.005106388	0.52554437	2.291886204	ADCY4//CXCL5//CXCL6//HCK//PF4V1//STAT3
hsa04061	Viral protein interaction with cytokine and cytokine receptor	4	0.010010388	0.52554437	1.999549072	CXCL5//CXCL6//PF4V1//TNFRSF10D
hsa04630	JAK-STAT signaling pathway	5	0.011756369	0.52554437	1.929726788	AOX1//LEP//PDGFRB//STAT3//STAT5A
hsa05416	Viral myocarditis	3	0.014071423	0.52554437	1.851661979	HLA-A//HLA-E//LAMA2
hsa04920	Adipocytokine signaling pathway	3	0.020418909	0.52554437	1.689967473	CPT1C//LEP//STAT3
hsa01230	Biosynthesis of amino acids	3	0.025393337	0.52554437	1.595280232	PGK1//PRPS2//PYCR1
hsa05133	Pertussis	3	0.026280353	0.52554437	1.58036881	CXCL5//CXCL6//SERPING1
hsa05169	Epstein-Barr virus infection	5	0.027237069	0.52554437	1.564839633	HDAC1//HLA-A//HLA-E//RUNX3//STAT3
hsa05203	Viral carcinogenesis	5	0.027237069	0.52554437	1.564839633	HDAC1//HLA-A//HLA-E//STAT3//STAT5A
hsa04612	Antigen processing and presentation	3	0.028103977	0.52554437	1.551232219	CD74//HLA-A//HLA-E
hsa04060	Cytokine-cytokine receptor interaction	6	0.037473107	0.525800484	1.426280294	CXCL5//CXCL6//GDF5//LEP//PF4V1//TNFRSF10D
hsa05330	Allograft rejection	2	0.040811779	0.525800484	1.389214476	HLA-A//HLA-E
hsa05323	Rheumatoid arthritis	3	0.04386683	0.525800484	1.35786375	CTSK//CXCL5//CXCL6
hsa05332	Graft-versus-host disease	2	0.046843799	0.525800484	1.329347889	HLA-A//HLA-E
hsa05414	Dilated cardiomyopathy (DCM)	3	0.04745307	0.525800484	1.32373569	ADCY4//EMD//LAMA2

KEGG, kyoto encyclopedia of genes and genomes.