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. 2021 Dec 9;12:731453. doi: 10.3389/fphar.2021.731453

TABLE 1.

Clinical outcomes of DPP4 inhibitors in COVID-19 patients with T2DM.

Reference Research type Country Sample size (users/non-users) Intensive care or mortality (users/non-users)
Solerte et al. (2020a) Retrospective Italy 338 (169/169) 18%/37%
J. H. Zhou et al., 2020b Retrospective China 444 (111/333) 1.8%/3.3%
Rhee et al. (2021) HIRA database Korea 832 (263/569) 3.4%/4.4%
NHIS database Korea 704 (175/529) 8%/11.5%
Y. Chen et al., 2020a Retrospective China 120 (20/100) 25%/14%
Mirani et al. (2020) Retrospective Italy 90 (11/79) 9.1%/46.8%
Wargny et al. (2021) Retrospective France 2794 (615/2179) 18.3%/21.3%
Fadini et al. (2020) Retrospective Italy 85 (9/76) 11.1%/13.9%
Noh et al. (2021) Cohort 586 (453/133) 10.4%/16.5%
Pérez-Belmonte et al. (2020) Retrospective Spain 1589 (180/1409) 41.7%/31.2%
Roussel et al. (2021) Cohort France 2449 (596/1853) 9.7%/11.7%
Silverii et al. (2021) Retrospective Italy 159 (13/146) 38.5%/37.0%
Israelsen et al. (2021) Retrospective Denmark 928 (284/644) 10.6%/3.3%
Cariou et al. (2020) Retrospective France 1317 (285/1032) 9.5%/10.9%

HIRA, health insurance review and assessment service; NHIS: national health insurance service.