Skip to main content
. 2021 Dec 9;8:735587. doi: 10.3389/fcvm.2021.735587

Table 7.

Median DSC and MBD of the average across leaflets, and p values for two–sided non–parametric Wilcoxon signed–rank test at individual stages and all stages combined.

FCN Configuration A FCN Configuration B Med. DSC A Med. DSC B p Value Med. MBD A Med. MBD B p Value
Pre–Stage1 (Two-Phase) Im-Only-Res (Two-Phase) Ann-Res 0.72[0.69–0.76] 0.81[0.76–0.83] 0.02* 0.59[0.49–0.66] 0.41[0.34–0.48] 0.03*
(Two-Phase) Im-Only-Res (Single-Phase) Com-Res 0.72[0.69–0.76] 0.81[0.80–0.81] 0.02* 0.59[0.49–0.66] 0.30[0.26–0.33] 0.02*
(Two-Phase) Im-Only-Res (Single-Phase) Ann-Com-Res 0.72[0.69–0.76] 0.85[0.82–0.86] 0.02* 0.59[0.49–0.66] 0.21[0.21–0.27] 0.02*
(Two-Phase) Ann-Res (Single-Phase) Com-Res 0.81[0.76–0.83] 0.81[0.80–0.81] 0.81 0.41[0.34–0.48] 0.30[0.26–0.33] 0.08
(Two-Phase) Ann-Res (Single-Phase) Ann-Com-Res 0.81[0.76–0.83] 0.85[0.82–0.86] 0.02* 0.41[0.34–0.48] 0.21[0.21–0.27] 0.03*
(Single-Phase) Com-Res (Single-Phase) Ann-Com-Res 0.81[0.80–0.81] 0.85[0.82–0.86] 0.02* 0.30[0.26–0.33] 0.21[0.21–0.27] 0.02*
Post–Stage1 (CSP) Im-Only-Res (CSP) Ann-Res 0.59[0.57–0.69] 0.74[0.65–0.79] 0.08 0.63[0.48–1.11] 0.44[0.38–0.60] 0.05*
(CSP) Im-Only-Res (Single-Phase) Com-Res 0.59[0.57–0.69] 0.67[0.63–0.70] 0.05* 0.63[0.48–1.11] 0.52[0.46–0.67] 0.05*
(CSP) Im-Only-Res (CSP) Ann-Com-Res 0.59[0.57–0.69] 0.76[0.70–0.79] 0.02* 0.63[0.48–1.11] 0.46[0.32–0.53] 0.02*
(CSP) Ann-Res (Single-Phase) Com-Res 0.74[0.65–0.79] 0.67[0.63–0.70] 0.38 0.44[0.38–0.60] 0.52[0.46–0.67] 0.81
(CSP) Ann-Res (CSP) Ann-Com-Res 0.74[0.65–0.79] 0.76[0.70–0.79] 0.05* 0.44[0.38–0.60] 0.46[0.32–0.53] 0.03*
(Single-Phase) Com-Res (CSP) Ann-Com-Res 0.67[0.63–0.70] 0.76[0.70–0.79] 0.08 0.52[0.46–0.67] 0.46[0.32–0.53] 0.22
Post–Stage2 (CSP) Im-Only-Res (CSP) Ann-Res 0.70[0.69–0.72] 0.74[0.70–0.75] 0.22 0.72[0.70–0.90] 0.67[0.64–0.74] 0.38
(CSP) Im-Only-Res (Two-Phase) Com-Res 0.70[0.69–0.72] 0.70[0.69–0.75] 0.22 0.72[0.70–0.90] 0.60[0.58–0.65] 0.05*
(CSP) Im-Only-Res (CSP) Ann-Com-Res 0.70[0.69–0.72] 0.76[0.73–0.80] 0.02* 0.72[0.70–0.90] 0.42[0.41–0.45] 0.02*
(CSP) Ann-Res (Two-Phase) Com-Res 0.74[0.70–0.75] 0.70[0.69–0.75] 1.00 0.67[0.64–0.74] 0.60[0.58–0.65] 0.30
(CSP) Ann-Res (CSP) Ann-Com-Res 0.74[0.70–0.75] 0.76[0.73–0.80] 0.03* 0.67[0.64–0.74] 0.42[0.41–0.45] 0.02*
(Two-Phase) Com-Res (CSP) Ann-Com-Res 0.70[0.69–0.75] 0.76[0.73–0.80] 0.02* 0.60[0.58–0.65] 0.42[0.41–0.45] 0.02*
Post–Stage3 (CSP) Im-Only (Two-Phase) Ann-Res 0.69[0.64–0.76] 0.79[0.78–0.80] 0.03* 0.98[0.74–1.54] 0.73[0.58–1.04] 0.38
(CSP) Im-Only (CSP) Com-Res 0.69[0.64–0.76] 0.80[0.78–0.82] 0.02* 0.98[0.74–1.54] 0.54[0.44–0.64] 0.02*
(CSP) Im-Only (Single-Phase) Ann-Com-Res 0.69[0.64–0.76] 0.84[0.83–0.85] 0.02* 0.98[0.74–1.54] 0.36[0.32–0.37] 0.02*
(Two-Phase) Ann-Res (CSP) Com-Res 0.79[0.78–0.80] 0.80[0.78–0.82] 0.30 0.73[0.58–1.04] 0.54[0.44–0.64] 0.02*
(Two-Phase) Ann-Res (Single-Phase) Ann-Com-Res 0.79[0.78–0.80] 0.84[0.83–0.85] 0.02* 0.73[0.58–1.04] 0.36[0.32–0.37] 0.02*
(CSP) Com-Res (Single-Phase) Ann-Com-Res 0.80[0.78–0.82] 0.84[0.83–0.85] 0.02* 0.54[0.44–0.64] 0.36[0.32–0.37] 0.02*
All Stages (CSP) Im-Only (CSP) Ann-Res 0.67[0.61–0.72] 0.77[0.73–0.81] <0.001* 0.78[0.60–1.12] 0.60[0.44–0.74] <0.001*
(CSP) Im-Only (Single-Phase) Com-Res 0.67[0.61–0.72] 0.78[0.68–0.81] <0.001* 0.78[0.60–1.12] 0.52[0.36–0.63] <0.001*
(CSP) Im-Only (CSP) Ann-Com-Res 0.67[0.61–0.72] 0.81[0.75–0.84] <0.001* 0.78[0.60–1.12] 0.38[0.30–0.46] <0.001*
(CSP) Ann-Res (Single-Phase) Com-Res 0.77[0.73–0.81] 0.78[0.68–0.81] 0.67 0.60[0.44–0.74] 0.52[0.36–0.63] 0.02*
(CSP) Ann-Res (CSP) Ann-Com-Res 0.77[0.73–0.81] 0.81[0.75–0.84] <0.001* 0.60[0.44–0.74] 0.38[0.30–0.46] <0.001*
(Single-Phase) Com-Res (CSP) Ann-Com-Res 0.78[0.68–0.81] 0.81[0.75–0.84] <0.001* 0.52[0.36–0.63] 0.38[0.30–0.46] <0.001*

The best ranked FCN input configurations across individual user inputs were compared. Different stages are presented along the larger row blocks. Metric values are displayed as median [IQR]. No additional user inputs (Im-Only), annular curve input (Ann), commissural landmarks input (Com) and resampling (Res). Significant p values (<0.05) marked with an asteroid (*). At individual stages of repair and all stages combined, the combination of annular curve input and commissural landmarks is significantly different from both the images only input and the annular curve only input. No significant difference could be found when comparing the annular curve only input and commissural landmarks only input.