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The major ion transporters located on the vacuolar membrane in C. albicans. V-ATPase, pumps H+ from the cytoplasm to the vacuole. Yvc1, transports Ca2+ from the vacuole to the cytoplasm. Pmc1, transports Ca2+ from the cytoplasm to the vacuole. Vcx1, the Ca2+/H+ exchanger. Ccc1, the vacuolar iron importer. Smf3, the vacuolar iron exporter. The arrows represent the direction of ion transport.
