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. 2021 Dec 9;12:779176. doi: 10.3389/fmicb.2021.779176

Table 1.

Genes encoding the subunits of V-ATPases and their null mutant phenotypes in C. albicans.

Subcomplexes of V-ATPase Subunits Encoding genes Phenotypes of null mutant References
Vacuolar acidification Hypal development Virulence in systematic infection
V1 A TFP1 Decreased Locked in yeast Avirulent Jia et al., 2014
B VMA2 Decreased Locked in yeast Avirulent Rane et al., 2014a
C VMA5 Decreased Locked in yeast Avirulent Zhang et al., 2017
D VMA8
E VMA4 Decreased Locked in yeast Avirulent Kim et al., 2019
F VMA7 Decreased Partial defect Avirulent Poltermann et al., 2005
G VMA10 Decreased Locked in yeast Avirulent Kim et al., 2019
H VMA13
Ve a VPH1 Decreased Partial defect Avirulent Kane, 2006
STV1 Uchanged Partial defect Virulent Kane, 2006
c VMA3 Decreased Locked in yeast Rane et al., 2014b
c' VMA11
c'' VMA16
d VMA6 Decreased Locked in yeast Avirulent Jia et al., 2018b
e C1_10750C_A