FIG. 3.

Clinical course of patients UPN85 and UPN93. (A) Patient UPN85 became positive in the shell-vial culture of peripheral blood. She also developed Aspergillus tracheobronchitis concomitantly under long-term steroid therapy for the treatment of acute GVHD and died of it on day 176. + and −, positive and negative in shell-vial culture, respectively. Open circles, white blood cells (WBC); solid circles, ANC; solid squares, plasma; solid triangles, whole blood. Bars and numbers show the number of CMV detected by the antigenemia assay. (B) Patient UPN93 died of grade III acute GVHD on day 60. Both patients responded well to ganciclovir. Results of real-time PCR for CMV accurately reflect their responses to the anti-CMV treatment.