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. 2021 Dec 9;15:775144. doi: 10.3389/fnhum.2021.775144

TABLE 5.

Univariate analysis of the correlation between cognition and Z drugs.

Z drug use (n = 42) Non-Z drug Use(n = 78) P-value
MMSE scores 28.00 (25.75, 29.00) 26.00 (23.00, 27.00) 0.003
MoCA scores 24.00 (19.00, 26.25) 22.00 (17.00, 23.00) 0.029
Long-term delayed recall of AVLT scores 7.00 (3.75, 9.75) 5.00 (4.00, 5.00) 0.037
TMT-B scores 85.00 (59.50, 217.00) 126.00 (90.00, 300.00) 0.073
BNT-30 scores 26.48 ± 3.13 25.00 ± 3.18 0.016
CDT scores 4.00 (3.00, 4.00) 4.00 (3.00, 4.00) 0.413
DST scores 5.00 (4.00, 5.00) 4.00 (2.00, 5.00 0.002
HAMD scores 10.19 ± 4.36 8.23 ± 4.32 0.020
HAMA scores 11.00 (7.00, 15.25) 9.00 (5.00, 11.00) 0.094
Male 18 (42.86%) 21 (26.92%) 0.075
Age (years) 59.43 ± 5.31 61.03 ± 6.70 0.184
Married/cohabitating 38 (90.48%) 71 (91.03%) 1.000
Living with others 40 (95.24%) 71 (91.03%) 0.637
Low income 18 (42.86%) 46 (58.97%) 0.091
Education (years) 12.24 ± 3.25 11.30 ± 3.49 0.154
BMI, kg/m2 23.03 ± 2.86 23.69 ± 2.75 0.220
Smoking,% 12 (28.57%) 11 (14.10%) 0.055
Concomitant illness
 Hypertension, % 14 (33.33%) 24 (30.77%) 0.773
 Diabetes mellitus, % 4 (9.52%) 13 (16.67%) 0.284
 Coronary heart disease, % 4 (9.52%) 8 (10.26%) 1.000
 Dyslipidemia, % 20 (47.62%) 27 (34.62%) 0.164
 Gout, % 0 (0.00%) 4 (5.13%) 0.337
Insomnia
 Age at onset (years) 48.00 (38.75, 54.00) 54.00 (30.00, 69.00) 0.213
 Insomnia duration (years) 10.00 (4.50, 17.75) 6.00 (2.00, 28.00) 0.755
 PSQI scores 14.05 ± 2.73 13.96 ± 2.84 0.873