Fig. 5.
Four-point bending mechanical testing results in E-modulus, ultimate load, and energy to failure on weeks 4 and 6 after distraction. The results showed a significant improvement in mechanical properties in GHSR3h. After being normalized to the contralateral intact tibia, ultimate load, energy to failure, and elastic modulus of the newly formed bone were all significantly increased compared to other groups. The mechanical properties of the new bone in Gclassic3h and GHSR1h were also enhanced compared to GHSR1/2h and Gcon, and no statistical difference was found between GHSR1/2h and Gcon. * vs control (Gcon), "#" vs classic signal three hrs/day (Gclassic3h), "^" vs high slew rate (HSR) signal 30 mins/day (GHSR1/2h), "&" vs HSR signal one hr/day (GHSR1h), p < 0.050. One-way analysis of variance and Tukey’s multi-comparison test were used for comparison of mean values.