Optimization of one-pot synthesis of naphthopyranopyrimidine 4a.

Entry	Catalyst (mol%)	T (°C)	Time (min)	Yielda (%)
1	—	100	300	0
2	ZnCl2 (2)	100	45	30
3	AlCl3 (2)	100	45	60
4	FeCl3 (2)	100	45	30
5	BiCl3 (2)	100	45	30
6	MnCl2 (2)	100	45	20
7	p-TSA (2)	100	45	50
8	NaHSO4 (2)	100	45	35
9	HNT (2)	100	45	30
10	[(PATDBP)Cl2@HNT] (2)	100	45	45
11	[(PATDBP)(HSO4)2@HNT] (2)	100	45	98
12	[(PATDBP)(HSO4)2@HNT] (1)	100	45	70
13	[(PATDBP)(HSO4)2@HNT] (4)	100	45	98
14	[(PATDBP)(HSO4)2@HNT] (2)	25	45	10
15	[(PATDBP)(HSO4)2@HNT] (2)	70	45	50
16	[(PATDBP)(HSO4)2@HNT] (2)	120	45	98

^aIsolated yields.