Table 1.
Male |
Quartiles of ASM%
|
P value | Female |
Quartiles of ASM%
|
P value | ||||||
Q1
|
Q2
|
Q3
|
Q4
|
Q1
|
Q2
|
Q3
|
Q4
|
||||
|
n
= 343 |
n
= 343 |
n
= 343 |
n
= 342 |
|
|
n
= 649
|
n
= 651
|
n
= 649
|
n
= 650
|
|
Age (yr) | 61.6 ± 8.8 | 63.2 ± 8.9a | 63.2 ± 8.9a | 69.4 ± 10.1a | < 0.001 | Age, yr | 60.8 ± 8.7 | 61.7 ± 8.8a | 62.9 ± 9.4a | 64.8 ± 9.7a | < 0.001 |
BMI (kg/m2) | 22.7 ± 2.9 | 24.3 ± 3.4a | 24.3 ± 3.4a | 25.6 ± 2.9a | < 0.001 | Weight, kg | 55.1 ± 8.1 | 58.0 ± 8.3a | 59.8 ± 8.6a | 62.6 ± 9.7a | < 0.001 |
WC, cm | 80.6 ± 9.1 | 85.8 ± 7.7a | 85.8 ± 7.7a | 91.7 ± 8.5a | < 0.001 | BMI, kg/m2 | 22.0 ± 2.7 | 23.5 ± 2.9a | 24.4 ± 3.1a | 26.0 ± 3.7a | < 0.001 |
FM, kg | 17.9 ± 4.6 | 20.3 ± 4.3a | 20.3 ± 4.3a | 24.5 ± 4.9a | < 0.001 | WC, cm | 76.4 ± 7.9 | 80.5 ± 8.6a | 82.8 ± 8.5a | 87.5 ± 9.4a | < 0.001 |
FM% | 22.4 ± 4.2 | 27.2 ± 3.2a | 27.2 ± 3.2a | 33.1 ± 3.3a | < 0.001 | FM, kg | 20.0 ± 4.1 | 22.5 ± 4.2a | 24.8 ± 4.8a | 27.6 ± 5.8a | < 0.001 |
ASM% | 32.6 ± 1.9 | 30.6 ± 1.0a | 30.6 ± 1.0a | 27.2 ± 1.6a | < 0.001 | FM% | 32.2 ± 3.9 | 36.3 ± 2.9a | 38.8 ± 3.0a | 42.4 ± 3.4a | < 0.001 |
SBP, mmHg | 129 ± 18 | 134 ± 17a | 134 ± 17a | 141 ± 19a | < 0.001 | ASM% | 27.7 ± 2.0 | 25.7 ± 0.8a | 24.5 ± 0.6a | 22.8 ± 1.1a | < 0.001 |
DBP, mmHg | 76 ± 11 | 78 ± 11a | 78 ± 11a | 77 ± 10 | 0.014 | SBP, mmHg | 129 ± 20 | 132 ± 19a | 135 ± 20a | 138 ± 19a | < 0.001 |
FBG, mmol/L | 5.4 ± 1.4 | 5.7 ± 1.7a | 5.7 ± 1.7a | 6.0 ± 1.7a | < 0.001 | DBP, mmHg | 72 ± 10 | 74 ± 10a | 75 ± 9 | 76 ± 10a | < 0.001 |
2hBG, mmol/L | 6.7 ± 2.5 | 7.6 ± 2.9a | 7.6 ± 2.9a | 8.9 ± 3.7a | < 0.001 | FBG, mmol/L | 5.3 ± 1.0 | 5.4 ± 1.2a | 5.5 ± 1.3a | 5.7 ± 1.7a | < 0.001 |
HOMA-IR | 1.2 (0.8-1.9) | 1.8 (1.2-2.5)a | 1.8 (1.2-2.5)a | 2.5 (1.7-3.9)a | < 0.001 | 2hBG, mmol/L | 6.8 ± 2.6 | 7.2 ± 2.5a | 7.7 ± 4.0a | 8.3 ± 3.4a | < 0.001 |
TG, mmol/L | 1.2 (0.9-1.8) | 1.4 (1.0-2.0)a | 1.4 (1.0-2.0)a | 1.6 (1.2-2.2)a | < 0.001 | HOMA-IR | 1.6 (1.0-2.3) | 1.8 (1.2-2.6)a | 2.1 (1.4-3.2)a | 2.3 (1.6-3.6)a | < 0.001 |
TC, mmol/L | 4.6 ± 0.8 | 4.7 ± 0.8a | 4.7 ± 0.8a | 4.7 ± 0.8a | 0.049 | TG, mmol/L | 1.2 (0.9-1.8) | 1.4 (1.0-2.0)a | 1.5 (1.1-2.1) | 1.6 (1.2-2.2)a | < 0.001 |
HDL-C, mmol/L | 1.40 ± 0.37 | 1.26 ± 0.29a | 1.26 ± 0.29a | 1.20 ± 0.25a | < 0.001 | TC, mmol/L | 5.2 ± 0.8 | 5.3 ± 0.9 | 5.3 ± 0.9 | 5.4 ± 1.0a | < 0.001 |
LDL-C, mmol/L | 2.59 ± 0.72 | 2.75 ± 0.74 | 2.75 ± 0.74 | 2.72 ± 0.72a | 0.004 | HDL-C, mmol/L | 1.64 ± 0.42 | 1.54 ± 0.37a | 1.48 ± 0.34 | 1.46 ± 0.33a | < 0.001 |
LFC% | 3.9 (1.9-7.8) | 5.0 (2.3-10.8)a | 5.0 (2.3-10.8)a | 6.3 (2.6-13.3)a | < 0.001 | LDL-C, mmol/L | 2.86 ± 0.75 | 3.02 ± 0.79a | 3.04 ± 0.83a | 3.14 ± 0.86a | < 0.001 |
NAFLD n (%) | 68 (19.9) | 107 (31.2)a | 107 (31.2)a | 141 (41.2)a | < 0.001 | LFC, % | 4.8 (2.5-9.7) | 5.8 (2.7-11.6)a | 5.9 (2.7-11.8)a | 7.1 (3.2-13.6)a | < 0.001 |
DM n (%) | 42 (12.3) | 81 (23.6)a | 81 (23.6)a | 123 (35.8)a | < 0.001 | NAFLD n (%) | 171 (26.3) | 214 (32.9)a | 219 (33.7)a | 275 (42.3)a | < 0.001 |
DM n (%) | 88 (13.6) | 106 (16.3) | 152 (23.4)a | 158 (24.3)a | < 0.001 |
P < 0.05, compared with Q1. The quartiles of ASM% were divided as follows: Male, (Q1, ≥ 32.0%; Q2, ≥ 30.5%-32.0%; Q3, ≥ 29.0%-< 30.5%; Q4: < 29.0%) and female, (Q1, ≥ 26.8%; Q2, ≥ 25.5% -< 26.8%; Q3, ≥ 24.3%-< 25.5%; Q4, < 24.3%).
BMI: Body mass index; WC: Waist circumference; FM: Fat mass; ASM: Appendicular skeletal muscle mass; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; FBG: Fasting blood glucose; 2hBG: 2-h postprandial blood glucose; HOMA-IR: Homeostasis model assessment for insulin resistance; TG: Triglycerides; TC: Total cholesterol; HDL-C: High-density lipoprotein-cholesterol; LDL-C: Low-density lipoprotein cholesterol; LFC: Liver fat content; NAFLD: Non-alcoholic fatty liver disease; DM: Diabetes mellitus.