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. 2021 Dec 15;12(12):2119–2129. doi: 10.4239/wjd.v12.i12.2119

Table 5.

Multivariate-adjusted associations of appendicular skeletal muscle mass (%) quartiles with diabetes mellitus in participants with different liver fat content, n (%)

LFC
DM
OR (95%CI, P value)
OR (95%CI, P value)
Male Unadjusted After adjusted
Q1 (n = 389) 82 (21.1) 0.635 (0.504-0.799, < 0.001) 0.308 (0.102-0.932, 0.032)
Q2 (n = 350) 66 (18.8) 0.540 (0.416-0.700, < 0.001) 0.184 (0.049-0.685, 0.012)
Q3 (n = 306) 74 (24.2) 0.760 (0.599-0.963, 0.023) 0.678 (0.158-2.908, 0.601)
Q4(n = 325) 116 (35.7) 0.830 (0.665-1.035, 0.099) 1.561 (0.440-5.539, 0.491)
Female
Q1 (n = 605) 84 (13.9) 0.828 (0.672-1.021, 0.077) 0.964 (0.311-2.990, 0.949)
Q2 (n = 642) 92 (14.3) 0.745 (0.609-0.913, 0.004) 0.517 (0.170-1.578, 0.247)
Q3 (n = 685) 118 (17.2) 0.739 (0.615-1.887, 0.091) 0.750 (0.274-2.048, 0.574)
Q4 (n = 667) 210 (31.5) 0.871 (0.750-1.011, 0.070) 1.122 (0.445-2.830, 0.808)

The quartiles of LFC were divided as follows: Q1: < 2.53%; Q2: ≥ 2.53%-< 5.52%; Q3: ≥ 5.52%- < 11.61%; Q4: ≥ 11.61%. Adjusted factors: Age, cigarette smoking, diabetes family history, FM, FM × ASM% quartiles, obesity, SBP, TG, HDL-C, and HOMA-IR. LFC: Liver fat content; DM: Diabetes mellitus; OR: Odds ratio; FM: Fat mass; ASM: Appendicular skeletal muscle mass; SBP: Systolic blood pressure; TG: Triglycerides; HDL-C: High-density lipoprotein-cholesterol; HOMA-IR: Homeostasis model assessment for insulin resistance.