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. 2021 Dec;191(12):2184–2194. doi: 10.1016/j.ajpath.2021.08.016

Figure 5.

Figure 5

Collagen XIV is a regulator of fibril assembly during stromal maturation. A and B: Collagen fibril diameters are slightly larger in the absence of collagen XIV (B) than in the wild-type C57BL/6 (WT) corneal stroma (A). C: The mean fibril diameter in the C57BL/6 cornea is 30.7 ± 3.8 nm, and fibrils have a mean diameter of 32 ± 3.5 nm in the absence of collagen XIV. D: The fibril density decreases significantly in Col14a1−/− stromas. n = 3 (both groups). ∗∗∗P < 0.001. Scale bars = 200 nm (A and B).