Figure 7.

Collagen XIV expression is recapitulated following stromal injury. A and B: Images demonstrating loss of collagen XIV expression at 1 week, shown by arrow (A), followed by re-expression of collagen XIV, shown by asterisks, at 3 weeks (B). C: Real-time PCR shows up-regulation of Col14a1 mRNA expression during wound healing. D: Heat map demonstrates the effects of collagen XIV in influencing matrix composition by fibroblasts expanded in vitro; protein from 40 corneas was used in this experiment, and 20 wild-type C57BL/6 (WT) and 20 Col14a1^−/− were used for in vitro expansion. n = 6 (A and B); n = 3 (C). ∗P < 0.05. En, endothelium; Ep, epithelium; St, stroma.