Table 1.
Summary of the age at onset, GAA triplet repeat expansion sizes and clinical features for all FRDA positive samples in group A.
| Patient no. | Age at onset | Expansion size, allele 1 | Expansion size, allele 2 | Summary of symptoms |
|---|---|---|---|---|
| 1 | 55 | 105 | 105 | Progressive gait ataxia, brisk lower limb reflexes, extensor plantars, dysarthria, reduced vibration sense |
| 2 | 50 | 120 | 120 | Cerebellar ataxia, very slowly progressive gait and truncal ataxia, mild dysarthria, impaired balance |
| 3 | 25 | 170 | 420 | Progressive gait ataxia, impaired balance, paresthesias in hands and feet, areflexia, reduced vibration and joint position sense, mild dysarthria, blackouts |