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. 2021 Apr 7;11(22):13061–13076. doi: 10.1039/d1ra01588e

Nano-MgFe2O4/Cu-catalysed reaction of styrene episulfide with phenylacetylene and sodium azide under different conditionsa.

graphic file with name d1ra01588e-u12.jpg
Entry MgFe2O4/Cu (g) Solvent Time (h) Temperature (°C) Yieldb (%)
1 H2O 11 60 0
2 0.005 H2O 5 60 40
3 0.01 H2O 5 60 75
4 0.02 H 2 O 2.5 60 96
5 0.03 H2O 2.4 60 96
6 0.02 CH3CN 3 82 50
7 0.02 EtOH 3 78 60
8 0.02 MeOH 3 65 60
9 0.02 EtOAc 3 77 65
10 0.02 DMF 3 100 55
11 0.02 THF 20 60 0
12 0.02 n-Hexane 20 68 0
13 0.02 CCl4 20 77 0
14 0.02 H2O 10 25 45
15 0.02 H2O 6 45 70
16c 0.02 H2O 4 60 Trace
17d 0.02 H2O 3 60 92
a

All reactions were carried out with styrene episulfide (1 mmol), phenylacetylene (1 mmol) and sodium azide (1.2 mmol).

b

Isolated yields.

c

Catalysed by MgFe2O4.

d

Catalysed by Cu nanoparticles.