Figure 5.

Examples of the comet assay results with MCT-1 cells stained with DAPI after treatment with no radiation (A), 3 Gy and High DMSO (B), and 6 Gy and 11 nM of rapamycin (RAPA) (C). The white arrows indicate cells designated as having extensively damaged DNA, showing a faint nucleus and paddle-shaped tail (brackets). Graphs show the percentage of MCT-1 cells that sustained extensive DNA damage 8 h and 24 h after exposure to 3 Gy (D) and 6 Gy (E) combined with RAPA and the percentage of MCT-2 cells that sustained extensive DNA damage 8 h and 24 h after exposure to 3 Gy (F) and 6 Gy (G) combined with RAPA.

n = 3. Error bars represent SEM.