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. 2021 Apr 12;11(22):13564–13570. doi: 10.1039/d1ra01816g

Substrate scope of bromolactonizationa.

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a

Reactions were conducted using a Retsch mixer mill (MM 400) in a 10 mL zirconium oxide chamber with alkenoic acid 1 (0.2 mmol) and NBS (0.22 mmol) at ambient temperature. The yields are isolated yields.