. 2021 Dec 8;6(50):35134–35143. doi: 10.1021/acsomega.1c06430

Table 2. Comparison of the Suzuki Reactions of Phenyl Chloride and 4-Tolylboronic Acid as Catalyzed Using Various Precatalysts^a^,^b.

entry	precatalyst	mol %	isolated yield (%)
1	POPd1-tolyl	1	15
2	POPd-tBu	2	72
3	POPd1-tBu	1	81
4	POPd2-tBu	1	70
5	POPd-Ad	2	99
6	POPd2-Ad	1	99

Phenyl chloride (0.5 mmol) and 4-tolylboronic acid (0.75 mmol) were used as substrates.

The optimized reaction conditions are shown in Scheme 4.

Table 2. Comparison of the Suzuki Reactions of Phenyl Chloride and 4-Tolylboronic Acid as Catalyzed Using Various Precatalystsa,b.