The selectivity of the two proposed sensors towards pioglitazonea.
| Interferentb | Selectivity coefficient (mean ± S.D.) | |||
|---|---|---|---|---|
| LC-ISE | SC-SP-ISE | |||
| Mannitol | 1.41 × 10−3 | ±0.65 | 8.32 × 10−4 | ±0.11 |
| Cellulose | 5.91 × 10−3 | ±0.78 | 6.98 × 10−4 | ±1.09 |
| Magnesium stearate | 7.91 × 10−3 | ±1.23 | 11.07 × 10−3 | ±0.56 |
| Talc | 6.81 × 10−3 | ±0.34 | 1.82 × 10−3 | ±0.88 |
| Lactose | 5.14 × 10−3 | ±0.44 | 3.83 × 10−4 | ±1.23 |
| Ferric oxide | 2.94 × 10−3 | ±0.89 | 2.81 × 10−3 | ±0.76 |
| Starch | 10.37 × 10−3 | ±1.20 | 9.93 × 10−3 | ±0.58 |
| Ca2+ | 11.07 × 10−3 | ±1.32 | 8.18 × 10−3 | ±0.90 |
| Mg2+ | 9.24 × 10−4 | ±0.77 | 5.19 × 10−4 | ±1.11 |
| Alogliptin benzoate | 8.86 × 10−3 | ±0.56 | 7.67 × 10−4 | ±0.67 |
Each value is the average of three determinations.
All interferents are in the form of 1 × 10−3 mol L−1 solution.