Table 2.

Overall Frailty Score and Other Factors Independently Associated with Single and Recurrent Falls Over 12 Months

	Single (vs. 0) Falls			Recurrent (vs. 0) Falls
	Adjusted Odds Ratio*	95% CI*	P value*	Adjusted Odds Ratio*	95% CI*	P value*
HIV Positive	1.05	0.70 – 1.57	0.81	0.95	0.63 – 1.44	0.82
Frailty Status
Pre-frail (frailty score 1–2)	0.97	0.66 – 1.43	0.87	2.23	1.40 – 3.57	0.0008
Frail (frailty score 3–5)	1.56	0.86 – 2.85	0.15	3.61	1.90 – 6.89	<0.0001
Age (per 10 years)	-	-	-	1.33	1.01 – 1.75	0.041
Marijuana use (ref=never)
Former	1.52	0.96 – 2.41	0.077	1.61	0.96 – 2.68	0.069
Current	2.26	1.34 – 3.82	0.0021	2.53	1.44 – 4.43	0.0012
Hypertension	-	-	-	0.61	0.41– 0.90	0.014
Cognitive complaints	-	-	-	2.02	1.23 – 3.32	0.0058
Depressive symptoms (modified CESD ≥15)	1.75	1.18 – 2.60	0.0055	2.51	1.69 – 3.72	<0.0001
# (up to 3) CNS active medication classes	1.29	1.07 – 1.54	0.0062	1.43	1.20 – 1.71	<0.0001

^*From multivariate logistic regression model that also includes study site.