ASO names and their sequences used in this studya.
ASO name | Sequence (5′-3′) | T m (°C) |
---|---|---|
ASO1 | 56.9 | |
ASO2 | 56.4 | |
ASO3 | 39.4 | |
ASO4 | 55.2 | |
ASO5 | 59.2 | |
ASO6 | 54.7 | |
ASO7 | 55.3 | |
ASO8 | 56.1 | |
ASO9 | 57.2 | |
ASO10 | 59.9 | |
ASO11 | 65.4 | |
ASO12 | 65.2 | |
Control 2′-OMe | 60.6 | |
Control 2′-MOE | 69.3 |
Red letters: DNA monomers, black letters: 2′-OMe monomers, blue letters: 2′-MOE monomers. All sequences were synthesized on a PS backbone. For Tm curves please see ESI Fig. S1.