. Author manuscript; available in PMC: 2023 Jan 1.

Published in final edited form as: Am J Ophthalmol. 2021 Jul 21;233:189–215. doi: 10.1016/j.ajo.2021.07.016

Table 5.

Characteristics of Patients Diagnosed with Plus Disease

Number of patients (% of ROP patients)	416	18.9%
Multiple Gestation (n, %)	75	18.0%	p = 0.236
Birth Weight

Mean, std dev (g)	670.2	160.4	p < 0.001^*
Proportion (n, %)
< 750g	298	75.8%	p < 0.001^#
751–1000g	76	19.3%
1001–1250g	18	4.6%
1251–1500g	-	0.0%
>1500g	1	0.3%
Gestational Age

Mean, std dev (weeks)	24.9	1.6	p < 0.001^*
Proportion (n, %)
<27w	346	87.4%	p < 0.001^ǂ
27–32w	47	11.9%
>32w	3	0.8%

t-test, birthweight and gestational age copmarison between patients with versus without diagnosis of plus disease

chi-square, incidence of plus disease in ROP infants with birthweight <750g versus >750g

^ǂ

chi-square, incidence of plus disease in ROP infants with gestational age <27w versus >27w

Abbreviations: BW - birthweight, g - grams, GA - gestational age, n - number, std dev - standard deviation, w - weeks