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. 2021 Apr 21;11(24):14686–14699. doi: 10.1039/d0ra07674k

Analysis of variance (ANOVA) for the BBD.

Source SS D f MS F-Value P-Value Status
Model 632.08 9 70.23 66.89 <0.0001 Significant
A – pH 3.13 1 3.13 2.98 <0.0001 Significant
B – NaCl 12.378 1 378.12 360.12 0.1451 Significant
C – extraction time 0.32 1 32.0 30.48 0.0027 Significant
AB 25.6 1 6.25 5.95 0.0587 Significant
AC 4.00 1 4.0 3.81 0.01084
BC 1.00 1 1.00 0.95 0.3799 Significant
A 2 174.52 1 174.52 166.21 <0.0001 Significant
B 2 42.06 1 42.06 40.05 0.0015 Significant
C 2 9.75 1 9.75 9.29 0.0285 Significant
Residual error 5.25 5 1.05
Lack-of-fit 3.25 3 1.08 1.08 0.5129 Not significant
Pure error 2.00 2 1.00
Total 637.33 14
R-squared 0.991
R-adjusted 0.976