Fig. 6. Electrostatic and steric coefficients for the field model. (A) Electrostatic coefficients superimposed to risperidone (used for the alignment, PD BID: 6a93) (up) and the most potent compounds in the training set (down). (B) Steric coefficients superimposed to risperidone (up) and the most potent compounds in the training set (down). (C) Contributions to predicted affinity for risperidone (up) and the most potent compounds in the training set (down).
