Table 3.

The relation with CVD events, prevalence and, PAF (%) of individual risk factors and the clusters.

Overall
	HR (95% CI)	Prevalence	PAF,%
None of the four risk factors	Reference	1.4	Reference
Current smoking	2.41 (0.81; 7.17)	28.2	28.4
Hypertension	1.30 (0.53; 3.18)	66.6	16.7
Dyslipidemia	1.25 (0.57; 2.70)	91.4	18.6
Overweight	1.78 (0.75; 4.23)	65.1	33.7
Smoking – Hypertension	3.17 (1.15; 8.74)	17.1	27.1
Smoking – Dyslipidemia	2.35 (1.08; 5.13)	27.1	26.8
Smoking – Overweight	1.11 (0.23; 5.36)	17.3	1.9
Hypertension – Dyslipidemia	1.95 (0.92; 4.14)	62	37.1
Hypertension – Overweight	1.40 (0.62; 3.17)	46.6	15.7
Dyslipidemia – Overweight	1.70 (0.80; 3.61)	60.6	29.8
Smoking – Hypertension – Dyslipidemia	4.06 (1.91; 8.63)	16.4	33.4
Smoking – Hypertension – Overweight	2.51 (0.93; 6.73)	11	14.2
Smoking – Dyslipidemia – Overweight	2.86 (1.33; 6.16)	16.4	23.4
Hypertension – Dyslipidemia – Overweight	1.99 (0.94; 4.18)	43.4	30.1
Smoking – Hypertension – Dyslipidemia – Overweight	3.25 (1.53; 6.88)	10.4	19.0

Reference group are patients (N = 174) with none of the four risk factors. Prevalence for each risk factor and cluster was calculated as number of patients in that cluster divided by the total amount of patients analyzed (n = 12,479), adding up the prevalence of clusters that also contain that specific risk factor combination (e.g. the 91.4% for L was based on L presence in the L individual risk factor, SL, LO, SHL, SLO, HLO and SHLO clusters). The PAF calculation was included in the method section.