Table 3.
Inhibition of cell attachment and biofilm development (at respective MIC values) on selected pathogens following exposure to CF6.
Cell Attachment (%) | ||||||
Compounds | S. pyogenes | S. aureus | E. coli | K. pneumoniae | P. aeruginosa | N. gonorrhoeae |
CF6 | 80.70 ± 0.10 | 77.62 ± 0.07 | 65.89 ± 0.23 | 40.76 ± 0.17 | 42.03 ± 0.39 | 81.19 ± 0.11 |
Ciprofloxacin | 84.33 ± 0.04 | 78.24 ± 0.02 | 76.80 ± 0.08 | 78.58 ± 0.19 | 79.79 ± 0.04 | 94.52 ± 0.01 |
Biofilm Development (%) | ||||||
Compounds | S. pyogenes | S. aureus | E. coli | K. pneumoniae | P. aeruginosa | N. gonorrhoeae |
CF6 | 29.08 ± 0.01 | 35.55 ± 0.14 | −4.65 ± 0.19 | 25.64 ± 0.19 | 25.28 ± 0.35 | 32.57 ± 0.35 |
Ciprofloxacin | 42.89 ± 0.04 | 42.36 ± 0.08 | 42.91 ± 0.03 | 43.62 ± 0.14 | 48.31 ± 0.07 | 40.72 ± 0.11 |