Table 3.

Undesirable outcomes included in the composite treatment failure instruments, along with the frequency in which they were utilised.

Components of the Composite Outcome Definitions	N (%)
Death	16 (59.3%)
Need for hospital admission/re-admission	14 (51.9%)
Need for treatment intensification	14 (51.9%)
Need for endotracheal intubation/mechanical ventilation	10 (37.0%)
Persistent or deteriorating symptoms and signs	8 (29.6%)
Need for non-invasive ventilation	3 (11.1%)
Need for urgent outpatient or emergency room visit	3 (11.1%)
New infection	3 (11.1%)
Need for higher level of hospital care	2 (7.4%)
Deteriorated arterial blood gases	1 (3.7%)
Hemodynamic instability	1 (3.7%)
Need for ICU admission	1 (3.7%)
Prolonged hospital stay	1 (3.7%)
Reduced level of consciousness	1 (3.7%)
Treatment intolerance	1 (3.7%)