Photomicrographs representing COX-2 immunoexpression in lung sections of adult male mice displaying: (A) in group I (control): very weak positive immunoreactions in the cytoplasm of the lining alveolar epithelial cells (arrows), (B): in group II (diseased): very strong positive immunoreactions in the cytoplasm of the alveolar epithelium (arrows), (C) in group III (diseased, 50 mg/kg FEE): many cells having strong positive immunoreaction (arrows), (D) in group IV (diseased, 100 mg/kg FEE): certain cells exhibit moderate strong immunoreactions (arrows), (E) in group V (diseased, 150 mg/kg FEE): few cells with very weak positive cytoplasmic immunoreaction (arrows) and (F) in group VI (150 mg/kg FEE only): few cells with very weak positive immunoreaction (arrows). [COX-2 immunostaining ×400, scale bar = 50 μm].