Figure 7.

Expression of mRNA of inflammation markers after poly (I:C)-primed airway ELV treatment in (a) brain tissue and (b) cultured rat microglial cells. Data are given as log2 Fold Change (2^−ΔΔCT) calculated from control specimens treated with unprimed ELVs. Statistical differences of markers expression between control specimens and specimens treated with poly (I:C)-primed airway ELVs calculated applying unpaired t-test; p < 0.05 considered significant. Bar plot represent mean of 3 experiments and whiskers—standard deviation; ns—not significant. Ifna is for interferon-alpha gene, Ifng—interferon-gamma, Ccl5—chemokine (C-C motif) ligand 5, or Rantes, Il1b—interleukin-1-beta, Tnf—tumour necrosis factor-alpha, Ptgs2—prostaglandin-endoperoxide synthase-2, Il6—interleukin-6, Ifnb1—interferon beta-1.