Table 1.
Baseline characteristics of patients included in control and intervention groups.
| Characteristics | Control Group (n = 125) |
Intervention Group (n = 188) |
p | |
|---|---|---|---|---|
| Comorbidities | Median Age | 69.8 (66.5–73.1) | 72.7 (70.2–75.1) | 0.906 |
| Gender male | 65 (52.0%) | 109 (58.0%) | 0.324 | |
| Diabetes mellitus | 31 (24.8%) | 42 (22.3%) | 0.645 | |
| Chronic renal insufficiency | 29 (23.4%) | 58 (30.8%) | 0.153 | |
| Chronic pulmonary disease | 20 (16.0%) | 40 (21.3%) | 0.258 | |
| Heart failure and cardiovascular diseases | 80 (64.0%) | 124 (66.0%) | 0.720 | |
| Immunosuppression | 24 (19.2%) | 28 (14.9%) | 0.324 | |
| Neoplasia | 44 (35.2%) | 73 (38.8%) | 0.524 | |
| Neutropenia | 7 (5.6%) | 10 (5.3%) | 0.919 | |
| Organ transplant | 7 (5.6%) | 4 (2.1%) | 0.104 | |
| Suspected source of bacteraemia | Urinary | 74 (59.2%) | 102 (54.3%) | 0.393 |
| Abdominal | 33 (26.4%) | 45 (23.9%) | 0.623 | |
| Respiratory | 10 (8.0%) | 20 (10.6%) | 0.447 | |
| Catheter | 4 (3.2%) | 11 (5.9%) | 0.420 | |
| Skin and soft tissue | 3 (2.4%) | 7 (3.7%) | 0.755 | |
| Other | 1 (0.8%) | 3 (1.6%) | 0.923 | |
| Microorganisms isolated | E. coli | 87 (69.6%) | 107 (56.9%) | 0.023 |
| ESBL E. coli | 10 (8.0%) | 14 (7.5%) | 0.866 | |
| K. pneumoniae | 18 (14.4%) | 25 (13.3%) | 0.785 | |
| ESBL K. pneumoniae | 0 (0%) | 4 (2.1%) | 0.262 | |
| P. aeruginosa | 2 (1.6%) | 4 (2.1%) | 0.936 | |
| Others | 8 (6.4%) | 34 (18.1%) | 0.003 |
ESBL: extended spectrum beta-lactamase; Bold letter: statistically significant.