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. 2021 Dec 15;10(12):1328. doi: 10.3390/biology10121328

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The tissue distribution of fenofibrate (FF) and fenofibric acid in mice following fenofibrate intraperitoneal injection (IP) and topical application of eye drops (ED). The fenofibrate and fenofibric acid levels were determined using LC-MS in tissues as indicated. (A–H) Left graph: The tissue distribution of fenofibrate. Right graph: The tissue distribution of fenofibric acid. The data were presented as mean ± SEM, analyzed by unpaired Student’s t test, n = 5–12 eyes or organs in each group.