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. 2021 Dec 7;9(12):1850. doi: 10.3390/biomedicines9121850

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Differentially expressed linear RNA. Venn diagrams showing the number of specific and common linear RNAs detected in groups RR-MC and HC (A), SP-MS and RR-MS (B), and SP-MS and RR-MS (C), respectively. The percentage of group-exclusive and common linear RNAs is calculated out of the total number of linear RNAs for each comparison and depicted in the corresponding section of the Venn diagram. Below, volcano plots showing the log2-fold change in expression and associated p-values between groups as denoted. The number of significantly upregulated and downregulated linear RNAs (FC > |1.5|; p-value < 0.05) are also shown in the upper right and upper left corners for the volcano plots, respectively.