Table 2.
Potential circRNA candidates to differentiate between RR-Ms and HC and between the two subtypes of MS. Id, log2-fold change value, p-adjusted value, if the transcript is expressed in both or in just one of the groups, position and gene symbol are shown.
| CircRNA Candidates RRMS vs. HC | ||||
| Position | Gene Symbol | Expr. in | log2 FC | p-adj |
| chr10:76153898-76158337 | ADK | both | 12.31 | 0.00242 |
| chr20:36361280-36365886 | CTNNBL1 | both | 11.34 | 0.00512 |
| chr5:80911291-80948145 | SSBP2 | both | 11.77 | 0.00906 |
| chr2:24777257-24807429 | NCOA1 | both | 11.70 | 0.00934 |
| chr19:50902107-50902741 | POLD1 | both | −10.63 | 0.01198 |
| chr3:129579782-129599402 | TMCC1 | HC | −24.32 | NA |
| chr8:98731276-98735263 | MTDH | HC | −29.98 | NA |
| chr1:151611363-151611595 | SNX27 | HC | −24.66 | NA |
| chr14:69588933-69616220 | DCAF5 | RRMS | 22.08 | NA |
| chr1:51869090-51874004 | EPS15 | RRMS | 9.51 | NA |
| chr9:115013208-115015068 | PTBP3 | RRMS | 24.97 | NA |
| chr10:25226112-25231365 | PRTFDC1 | RRMS | 10.40 | NA |
| chr2:219394678-219411021 | USP37 | RRMS | 10.58 | NA |
| CircRNA Candidates RRMS vs. SPMS | ||||
| Position | Gene Symbol | Expr. in | log2 FC | p-adj |
| chr10:76153898-76158337 | ADK | Both | 12.34 | 0.00172 |
| chr15:89856134-89857938 | FANCI | Both | −10.64 | 0.00683 |
| chr20:36361280-36365886 | CTNNBL1 | Both | 10.75 | 0.00794 |
| chr7:77200394-77221573 | PTPN12 | Both | 10.26 | 0.00818 |
| chr18:76886266-76914555 | ATP9B | Both | −9.95 | 0.01702 |
| chr1:1735857-1756938 | GNB1 | RRMS | 10.07 | NA |
| chr16:53288349-53308214 | CHD9 | RRMS | 9.69 | NA |
| chr18:18586311-18588155 | ROCK1 | RRMS | 9.19 | NA |
| chr19:30476129-30477324 | URI1|C19orf2 | RRMS | 9.17 | NA |
| chr3:125216184-125223588 | SNX4 | RRMS | 8.59 | NA |
| chr18:67534592-67535352 | CD226 | SPMS | −37.13 | NA |
| chr4:56265252-56269505 | TMEM165 | SPMS | −23.24 | NA |