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. 2021 Oct 29;322(1):H44–H56. doi: 10.1152/ajpheart.00255.2021

Figure 2.

Figure 2.

A: representative ultrasound image showing ascending aorta of 9-mo Het male mouse. Arrows show diameter measurement points at each region. Graphs show means and standard deviation for diameter of ascending aorta of WT and Het male and female mice at proximal (B) and distal ascending aorta (C) over a time course of 3–12 mo. White circles, Het mice; black circles, WT mice. Using three-way ANOVA for n = 80 (5 mice per study group), * and ** indicate significant differences between genotypes at P < 0.05 and P < 0.01, respectively. & and @ indicate significantly smaller diameter compared with 9 and 12 mo, respectively, for same sex and genotype. Letters next to each graph indicate dependency and interactions. A, age; A&G: age and genotype; G, genotype; LV, left ventricle; S, sex; WT, wild type.