Table 1.

Detailed characteristics of discarded grafts undergoing normothermic machine perfusion

	Adequate Hepatocellular Function (n = 3 subjects)			Inadequate Hepatocellular Function (n = 3 subjects)			P Value
Liver no.	F1	F2	F3	N1	N2	N3
Total WIT, min	28	24	33	23	26	70	0.83
Functional WIT, min	8	8	12	11	9	11	0.50
CIT, h	11.6	5	7.6	6	13.1	6.1	0.83
Donor age, yr	60	58	59	55	21	56	0.0495
Sex	F	M	M	F	M	F	0.50
BMI, kg/m2	24.5	28.3	27.3	24.6	27.4	44	0.51
Macrosteatosis, %	0	5	2	0	0	0	0.12
Microsteatosis, %	10	0	0	0	0	0	0.32
AST, U/L	39	41	57	24	82	138	0.51
ALT, U/L	27	22	38	11	97	161	0.51
Total bilirubin, mg/dL	0.6	0.9	0.4	0.2	0.4	0.4	0.10
ALP, U/L	95	36	31	94	234	494	0.13

Macrosteatosis defined as large droplet steatosis with nuclear displacement, provided as % of entire tissue field evaluated. Microsteatosis defined as small droplet steatosis without nuclear displacement, provided as % of entire tissue field evaluated. Aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin, and alkaline phosphatase (ALP) levels indicate last available values before procurement. Group comparisons made using the Wilcoxon rank-sum (Mann–Whitney U) or Fisher’s exact test, where appropriate. BMI, body mass index (kg/m²); CIT, cold ischemic time in minutes; F, female; M, male; WIT, warm ischemic time in minutes. Boldface value is a significant P value.