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. 2021 Dec 18;9(12):1942. doi: 10.3390/biomedicines9121942
TCA tricarboxylic acid
OXPHOS oxidative phosphorylation
PPP pentose phosphate pathway
ROS reactive oxygen species
ATP adenosine triphosphate
ADP adenosine bisphosphate
ETC electron transport chain
NADH nicotinammina adenina dinucleotide
PGC1α peroxisome proliferator activated receptor gamma coactivator-1α
HIFA hypoxia inducible factor alpha
MnSOD manganese-requiring mitochondrial enzyme
Trx thioredoxin
TrxR thioredoxin reductase
Prx3 peroxidase 3
NRF2 nuclear factor erythroid- 2–related factor 2
GSH reduced glutathione
GSSG oxydited glutathione
BPTES bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-ylethyl sulfide
Bcl-2 B-cell lymphoma 2
2DG glycolysis inhibitor 2-Deoxy-D-glucose
GLUT glucose transporters
G1P glucose-1-phosphate
G6P glucose-6-phosphate
HK2 hexokinase 2
PFK phosphofructokinase
DHAP dihydroxyacetone phosphate
GAPDH glyceraldehyde-3-phosphate-dehydrogenase
PGAM1 phosphoglycerate mutase 1
PK pyruvate kinase
LDH lactate dehydrogenase
HIF-1α hypoxia-inducible factor 1α
CoA acetyl coenzyme A
TME tumor microenvironment
CTCs circulating tumor cells
cfDNA cell-free DNA
HRE hypoxia response element
MSR magnetic resonance spectroscopy
V-ATPase vacuolar H+-ATPase
NHE Na+/H+ exchanger
MCTs monocarboxylate transporters
CA-IX/XII carbonic anhydrase IX/XII
NBCs Na+/HCO3 co-transporters
PPIs Proton Pumps Inhibitors
CAFs cancer-associated fibroblasts
CAV1 Caveolin-1 NF-kB
NF-kB nuclear factor kappa-light-chain-enhancer of activated B cells
TIGAR TP53 Induced Glycolysis and Apoptosis Regulator
TNF tumor necrosis factor
MOMP outer mitochondrial membrane
AKT serine/threonine kinase
PUMA p53 upregulated modulator of apoptosis
MCL-1 Myeloid leukemia 1
HCQ hydroxychloroquine
Vps34 class III phosphatylinositol 3-kinase
ULK1 autophagy initiating kinases
TLRs toll-like receptors
IFN interferon
RIP receptor-interacting protein
Nec-1 Necrostatin-1
TNFR1 tumor necrosis factor receptor 1
TRADD TNFR-associated death domain
PYGL glycogen phosphorylase
PDH pyruvate dehydrogenase
PRRs pattern recognition receptors
TCRs T cell receptors
GPX4 glutathione-dependent peroxidase 4
DFO chelator deferoxamine
NAC the antioxidant N-acetyl-cysteine
PCL Polygonatum cyrtonema lectins
TFR1 iron specific receptor
Mfrn1 mitoferrin 1
Mfrn2 mitoferrin 2
VDACs voltage-dependent anion channels
ER endoplasmic reticulum
FADD Fas Associated Via Death Domain
Bcl-XL B-cell lymphoma-extra large
Bax BCL2 Associated X
Bad BCL2 Associated Agonist of Cell Death
tBid truncated BH3 Interacting Domain Death Agonist
PI3K Phosphoinositide 3-kinase
AKT serine/threonine kinase
MLKL Mixed lineage kinase domain-like protein
DAMPS Damage-associated molecular patterns
AMPK AMP-activated protein kinase
mTOR mammalian target of rapamycin
FLIP Cellular FLICE-like inhibitory protein
LC3 Microtubule-associated protein 1A/1B-light chain
DMT11 Divalent metal transporter-1