Figure 4.

Functional categories of the androgen-responsive proteome. The regulated proteins fall into 10 major functional categories, as shown in the outer squares. The consensus kinetic curves of its members, as shown in clustering analysis, were drawn in proportion to the number of proteins in each cluster. The clusters that have a significantly large number of proteins were only presented (p-value < 0.05). In the inner square, the protein–protein interactions between functional categories are displayed. A line is drawn between any two categories if more than 5% of their member proteins interact. The red line signifies a large number of interactions between two clusters (p-value < 0.05).