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Ligands and functions of different integrins of human leukocytes (RGD, Arg-Gly-Asp sequence; VCAM-1, vascular cellular adhesion molecule-1; ICAM-1, Intercellular adhesion molecule-1) [10,30,31,32,33].
| Integrin | Ligands | Functions |
|---|---|---|
| β1 | RGD, VCAM-1, E-cadherin | Adhesion |
| β2 | iC3b, fibrinogen, ICAM-1 | Adhesion, phagocytosis, apoptotic cell clearance |
| β6 | RGD, fibronectin | Adhesion, endocytosis, inflammation |
| β7 | RGD, VCAM-1 | Adhesion, inflammation |
