Table 3.
MICs/MBCs (μM) of t-DPH1 and its analogues against different microorganisms.
| t-DPH1 | t-DPH1-K4 | t-DPH1-5K | t-DPH1-6K | t-DPH1-6KW | |
|---|---|---|---|---|---|
| S. aureus (ATCC 6538) | 8/16 | 2/4 | 2/2 | 4/8 | 128/128 |
| Methicillin-resistant Staphylococcus aureus (MRSA) (NCTC 12493) | 16/32 | 2/4 | 2/4 | 32/64 | 128/256 |
| Enterococcus faecalis (E. faecalis) (NCTC 12697) | 128/256 | 32/32 | 8/16 | 256/512 | 512/>512 |
| E. coli (ATCC 8739) | 2/4 | 1/2 | 2/4 | 2/4 | 2/4 |
| K. pneumoniae (ATCC 43816) | 8/16 | 2/4 | 2/4 | 4/8 | 64/64 |
| P. aeruginosa (ATCC 9027) | 16/32 | 8/16 | 4/8 | 8/16 | 64/128 |
| C. albicans (ATCC 10231) | 64/128 | 32/64 | 256/512 | 64/128 | 512/>512 |