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. 2021 Nov 30;11(12):1794. doi: 10.3390/biom11121794

Figure 6.

Figure 6

The potential of ERG as a co-target with BRD9. (A) Gene network map showing the associations between BRD9 and ERG. (B) Scatterplot with line of best fit showing the correlation between BRD9 and ERG expression in the TCGA cohort. (C) Violin plot showing BRD9 expression in who patients were ERG (TMPRSS2-ETS fusion) positive (right) and negative (left) in the Barbieri cohort. p-value was obtained using a Mann Whitney U test. (D) Violin plot showing BRD9 expression in who patients were ERG positive (right) and negative (left) in the Gerhauser cohort. p-value was obtained using a Mann Whitney U test. (E) Violin plot showing BRD9 expression in who patients were ERG positive (right) and negative (left) in the Taylor cohort. p-value was obtained using a Mann Whitney U test. (F) Violin plot showing BRD9 expression in who patients were ERG positive (right) and negative (left) in the Abida cohort. p-value was obtained using a Mann Whitney U test. (G) Stacked bar chart showing BRD9 mutation distribution in patients who were ERG positive and negative and the number of patients in each sample in the Abida cohort. p-value was obtained using Fisher’s exact test. Y axis scales on violin plots vary due to experimental variation. Gene network map created using https://genemania.org/. (accessed on 19 April 2021).