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. 2021 Dec 14;9(12):1909. doi: 10.3390/biomedicines9121909

Table 4.

Major enzymatic ROS scavengers in the antioxidant mechanisms. RX = redoxin, DHA = dehydroascorbate, AsA = ascorbate, MDHA = monodehydroascorbate. Adapted from ref. [8].

Scavenger Acronym Catalyzed Reaction
Superoxide dismutase SOD M(n+1)++SOD+O2Mn++SOD+O2Mn++SOD+O2+2H+M(n+1)++SOD+H2O2
Catalase CAT 2H2O2O2+2H2O
Ascorbate peroxidase APX H2O2+AsADHA+2H2O
Monodehydroascorbate reductase MDHAR MDHA+NAD(P)HAsA+NAD(P)+
Glutatione peroxidase GPx 2GSH+H2OGSSG+2H2O2GSH+ROOHGSSG+ROH+H2O
Glutatione transferase GST RX+GSHHX+R-S-GSH