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. 2021 Nov 28;9(12):1785. doi: 10.3390/biomedicines9121785

Figure 2.

Figure 2

Summary of trifluoperazine’s anti-tumor mechanism of action. Key: GSK-3, Glycogen synthase kinase-3; p-AKT, Phosphorylated Akt, PD-L1, Programmed death-ligand 1; FOXO1, Forkhead Box O3; MDR, Multiple drug resistance; GBM, glioblastoma.