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. 2021 Nov 30;9(12):1802. doi: 10.3390/biomedicines9121802

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Gene expression profiles of pro-inflammatory cytokine genes and growth factor genes after 6 h and heat shock protein gene transcript levels after 12 h as well as desmoglein gene and AMP gene expression after 48 h for HaCaT keratinocyte scratches treated with wIRA, heating w/o wIRA and UV-B irradiation. Hashtags [#] designate significant differences of scratch wound healing or transcription levels at the respective time point compared to the control under optimal conditions (# p < 0.05, ## p < 0.01, ### p < 0.001) while the plus sign [+] specifies significant differences between wIRA-treated samples and those receiving heating w/o wIRA under non-optimal conditions at the respective time point (+ p < 0.05, ++ p < 0.01).