Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 2;9(12):1817. doi: 10.3390/biomedicines9121817

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Identification of common DEGs in all MTZ-R T. vaginalis strains compared with the MTZ-S group treated with or without MTZ. Venn diagram showing the number of genes shared by three MTZ-R T. vaginalis strains (Tv_50142, Tv50143, and Tv30238) whose expression is upregulated (A) and downregulated (B) in comparison with three MTZ-S strains (Tv-30001, Tv-30236, and Tv50148). Upon MTZ treatment, the number of upregulated (C) and downregulated (D) genes among the identical MTZ-R strains in comparison with the MTZ-S strains were also analyzed. The gene expression patterns of DEGs in all MTZ-R strains compared with those of MTZ-S in the presence or absence of MTZ were analyzed by cluster analysis and shown as heatmaps. Genes shown in red and purple color indicate upregulation and downregulation, respectively. MA plots represent the expression levels (baseMean) and expression changes (log2 fold change in normalized counts values) in the corresponding DEGs.