Figure 3.

Joint activities of oral and vaginal probiotics and LF in the prophylaxis and cure of feminine genital tract infection and inflammation. Prebiotic and antimicrobial activities of LF are complementary. LF, via several means, destroys/inhibits the growth of pathogenic microorganisms and, at the same time, promotes the growth of symbiotic microorganisms, thus normalizing the composition of the vaginal microbiota. LF has beneficial effects on resident symbiotic bacteria and exogenous probiotic bacteria when applied orally and vaginally. LF is advantageous for the activity of probiotics. Probiotics, in turn, act enzymatically on LF by degrading the protein into more active peptides (lower left part), ↑ increase, ↓ decrease.