Table 1.
Demographic characteristics and blood biochemical parameters of included patients with amyotrophic lateral sclerosis (ALS) and age- and sex-matched normal controls (NCs).
| NC (n = 36) | ALS (n = 36) | |
|---|---|---|
| Age (years) | 57.89 ± 6.51 | 57.31 ± 9.86 |
| Male (%) | 21 (0.58%) | 21 (0.58%) |
| BMI * | 25.22 ± 3.64 | 21.36 ± 4.52 |
| Triglyceride (mg/dL) | 131.33 ± 78.54 | 107.16 ± 49.21 |
| Cholesterol (mg/dL) | 198.42 ± 65.19 | 184.99 ± 52.96 |
| HDL (mg/dL) | 48.48 ± 17.45 | 54.55 ± 16.44 |
| LDL (mg/dL) | 121.16 ± 49.52 | 115.77 ± 36.65 |
| Pre-prandial glucose (mg/dL) | 106.14 ± 46.05 | 95.89 ± 11.48 |
| Glycohemoglobin (%) | 6.04 ± 2.00 | 5.67 ± 0.64 |
| Diabetes (%) | 4 (11.11%) | 5 (13.89%) |
| Time between symptom onset and blood draw (years) | 2.89 ± 3.49 | |
| Family history of ALS (%) | 1 (2.78%) | |
| Riluzole (%) | 18 (50%) | |
| ALSFRS-r | 27.14 ± 13.93 | |
| Onset subtype | ||
| Spinal | 33 (91.67%) | |
| Bulbar | 2 (5.56%) | |
| Respiratory | 1 (2.78%) |
ALSFRS-r: revised Amyotrophic Lateral Sclerosis Functional Rating Scale; BMI: body mass index; HDL: high-density lipoprotein; LDL: low-density lipoprotein. *: Significant difference between NC and ALS. p < 0.05. Two-tailed Student’s t-test.