| ACE | angiotensin-converting enzyme inhibitors |
| AII | angiotensin II |
| APKD | autosomal polycystic kidney disease |
| AS | alport syndrome |
| ASO | antisense oligonucleotide |
| ATP | adenosine triphosphate |
| CKD | chronic kidney disease |
| COL4A5 | collagen IV alpha-5-chain |
| ccRCC | clear cell renal cell carcinoma |
| DMPK | disposition, metabolism and pharmacokinetics |
| ECM | extracellular matrix |
| EMA | european medicines agency |
| FDA | federal drug administration |
| GFR | glomerular filtration frate |
| GLUT1 | glucose uptake transporter 1 |
| HIF | hypoxia inducible factor |
| ICI | immune check-point inhibitors |
| IL-6 | interleukin-6 |
| ITF | intra tumor fibrosis |
| miRNA | micro ribonucleic acid |
| mRNA | messenger ribonucleic acid |
| mTOR | mammalian target of rapamycin |
| Na/K-ATPase | sodium/potassium ATPase |
| NF-kB | nuclear factor-kappa B |
| NGAL | neutrophil gelatinase-associated lipocalin |
| NRF2 | nuclear factor erythroid 2-related factor 2 |
| PHD | prolyl hydroxylase |
| PROTAC | proteolysis targeting chimeras |
| RCC | renal cell carcinoma |
| RPTEC | renal proximal tubule epithelial cells |
| SLGT2 | sodium glucose transport protein 2 |
| TGF-β | transforming growth factor beta |
| TKI | tyrosine kinase inhibitor |