Table 3.
Comparisons of surgical outcomes between patient groups stratified by the time to surgery in patients with PAP (n = 91).
| Variables | Within 2 Weeks (n = 32) |
After 2 Weeks (n = 59) |
p-Value | Within 3 Weeks (n = 51) |
After 3 Weeks (n = 40) |
p-Value | Within 4 Weeks (n = 62) |
After 4 Weeks (n = 29) |
p-Value |
|---|---|---|---|---|---|---|---|---|---|
| Moderate to severe pancreatitis | 7 (21.9%) | 18 (30.5%) | 0.378 | 12 (23.5%) | 13 (32.5%) | 0.341 | 14 (22.6%) | 11 (37.9%) | 0.126 |
| Preop. ERCP | 17 (53.1%) | 31 (52.5%) | 0.958 | 28 (54.9%) | 20 (50.0%) | 0.642 | 35 (56.5%) | 13 (44.8%) | 0.301 |
| CRP, preop. max. | 4.6 | 5.1 | 0.753 | 4.8 | 4.9 | 0.931 | 4.2 | 6.6 | 0.158 |
| immediate preop. | 2.2 | 2.1 | 0.869 | 2.3 | 1.9 | 0.576 | 2.1 | 2.2 | 0.910 |
| Pathology, pancreatic tumors | 22 (68.8%) | 41 (69.5%) | 0.942 | 35 (68.6%) | 28 (70.0%) | 0.888 | 43 (69.4%) | 20 (69.0%) | 0.970 |
| Operation time (mins) | 324.0 | 315.9 | 0.603 | 325.1 | 310.6 | 0.335 | 322.4 | 310.9 | 0.473 |
| Pancreatic texture, soft | 4 (12.5%) | 9 (15.3%) | >0.99 | 8 (15.7%) | 5 (12.5%) | 0.666 | 8 (12.9%) | 5 (17.2%) | 0.749 |
| Operation failure | 1 (3.1%) | 5 (8.5%) | 0.419 | 4 (7.8%) | 2 (5.0%) | 0.691 | 4 (6.5%) | 2 (6.9%) | >0.99 |
| Exploration only | 0 (0%) | 2 (3.4%) | 0.539 | 1 (2.0%) | 1 (2.5%) | >0.99 | 1 (1.6%) | 1 (3.4%) | 0.538 |
| Conversion to TP | 1 (3.1%) | 3 (5.1%) | >0.99 | 3 (5.9%) | 1 (2.5%) | 0.628 | 3 (4.8%) | 1 (3.4%) | >0.99 |
| C-D grade ≥ III complications | 4 (12.5%) | 12 (20.3%) | 0.348 | 8 (15.7%) | 8 (20.0%) | 0.592 | 11 (17.7%) | 5 (17.2%) | 0.953 |
| CR-POPF | 1 (3.1%) | 4 (6.8%) | 0.653 | 1 (2.0%) | 4 (10.0%) | 0.165 | 4 (6.5%) | 1 (3.4%) | >0.99 |
| Postoperative hemorrhage | 1 (3.1%) | 4 (6.8%) | 0.653 | 4 (7.8%) | 1 (2.5%) | 0.380 | 4 (6.5%) | 1 (3.4%) | >0.99 |
| Intra-abdominal infection | 5 (15.6%) | 5 (8.5%) | 0.313 | 7 (13.7%) | 3 (7.5%) | 0.503 | 8 (12.9%) | 2 (6.9%) | 0.493 |
| Biliary fistula | 0 (0%) | 1 (1.7%) | >0.99 | 1 (2.0%) | 0 (0%) | >0.99 | 1 (1.6%) | 0 (0%) | >0.99 |
| Chyle leak | 4 (12.5%) | 3 (5.1%) | 0.236 | 4 (7.8%) | 3 (7.5%) | >0.99 | 5 (8.1%) | 2 (6.9%) | >0.99 |
| Surgical site infection | 0 (0%) | 2 (3.4%) | 0.539 | 0 (0%) | 2 (5.0%) | 0.190 | 0 (0%) | 2 (6.9%) | 0.099 |
| Delayed gastric emptying | 4 (12.5%) | 2 (6.8%) | 0.445 | 5 (9.8%) | 3 (7.5%) | >0.99 | 7 (11.3%) | 1 (3.4%) | 0.428 |
| Length of stay (days) | 13.4 | 12.8 | 0.737 | 13.9 | 11.9 | 0.227 | 13.7 | 11.5 | 0.179 |
| 90-day re-admission | 3 (9.4%) | 8 (13.6%) | 0.741 | 6 (11.8%) | 5 (12.5%) | >0.99 | 7 (11.3%) | 4 (13.8%) | 0.739 |
Abbreviations: PAP—preoperative acute pancreatitis; Preop.—preoperative; ERCP—endoscopic retrograde cholangiopancreatography; Max.—maximal; TP—total pancreatectomy; C-D—Clavien-Dindo; CR-POPF—clinically relevant postoperative pancreatic fistula.